Hypodermic
The first recorded use of a hypodermic syringe to inject drugs was in 1853.[1]
References
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Philip G. Boysen; Jenilkumar H. Patel; Angelle N. King (2023). "Brief History of Opioids in Perioperative and Periprocedural Medicine to Inform the Future". Ochsner Journal. 23 (1): 43–49. doi:10.31486/toj.22.0065. ISSN 1524-5012. Retrieved 2026-05-08.
Facilitating the administration of opioids, Irish physician Francis Rynd introduced the hollow needle in 1844 to treat a patient's acute facial pain. In an account of the successful operation, Rynd wrote that the patient's pain ceased within a minute of the treatment. French physician Charles-Gabriel Pravaz introduced the piston syringe in 1853. Pravaz's syringe was designed for injecting coagulant into aneurysms, but it was modified and used for the administration of drugs. Scottish physician Alexander Wood used the hypodermic syringe to inject morphine hydrochloride into patients, and he noted a remarkably rapid effect of the treatments. These devices made controlled dosing of drugs, including opioids, possible.