Opium

Opium is a drug made from the sticky sap in the flowers of the poppy plant. It is a mix of several dozen biologically active opioid compounds. It is made mainly in Afghanistan, Pakistan, and the area around Cambodia, Laos, and Thailand. It can be further processed into morphine.

Opium was popular in China in the 19th century and the British profited selling it there, enforcing their desire to sell opium with military expeditions against the Chinese.