Orphines
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Orphines are a powerful sub-class of opiods, synthetic drugs that are designed to work like opium, and drugs refined from opium.[1] They are more addictive, more powefful and more dangerous than Fentanyl.
References
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Jan Hoffman (2026-05-04). "What to Know About Orphines, a New Class of Deadly Opioids". p. A19. ISSN 0362-4331. Retrieved 2026-05-17.
They are a class of opioids that was created in the 1960s by Paul Janssen, a Belgian doctor and pharmacologist, whose teams investigated rapid, safe pain relievers for surgery. As part of that effort, they also developed fentanyl.